Barriers to the adoption of EHR (EHR) systems have been well documented. Researchers and practitioners agree that the benefits of EHR systems are contingent on MU (MU) of EHR. However, most research on the barriers to MU (set of standards defined by Centers for Medicare & Medicaid Services) is a theoretical and anecdotal. Despite industry wide agreement on the benefits of EHR and other forms of health information technology, health care providers have moved slowly to adopt these technologies. Whether or not physicians support and use EHRs will have a great influence on other user groups in a medical practice, such as nurses and administrative staff. The research objective for this paper is to understand the impact of IT Culture Conflict on MU Resistance and the direct effect of User Involvement and indirect effect of Trusting Belief in IT Artifacts. Implications for research and practice are discussed.