This paper presents industry and organizational factors that were found to play an important role in dictating IT’s strategic impact on and contribution to its enterprise. Five IT executives from different industries were interviewed about their firms’ investment in people, process and technology in executing operations, investment and strategy. The firms’ IT organizations were categorized using McFarlan’s Strategic Grid for IT. The recurring key themes revealed by the IT executives centered on People, Relationship Management, Stakeholder Management, and Strategic Planning. In addition, key observations about factors that influence IT’s approach in its partnering with the business were discussed. These factors are organization breadth and size, the nature in which the firms’ customer contact was managed through IT, and the influence of cloud/Software-as-a-Service offerings on IT’s approach to addressing business needs.