Research on e-learning has been conducted over the past several decades. The most common e-learning empirical research streams have been studies that examine potential predictors of course learning outcomes. Building a holistic success model with a system’s view is a critical issue that must be tackled to make progress toward building robust e-learning theories. The purpose of this research is to further investigate the critical issue raised by Eom and Ashill (2018) to guide future empirical research in building robust e-learning theories. The majority of e-learning empirical research studies of critical success factors over the past decade built models of a set of disconnected constructs. We conclude that it is imperative for future e-learning empirical research to focus on building a holistic success model of a set of interconnected constructs with a system’s view.