This paper presents aspects of the design, development and implementation of an open e-learning resource (OER) on anti-plagiarism. This course is designed to be delivered as distance learning to students in Higher Educational Institutions. It is based on a synchronous e-learning platform; it includes thematic lectures, a variety of asynchronous tools for communication and support of the learners, game-based learning activities and gamification elements. Through its pilot implementation, learners acquired valuable knowledge in anti-plagiarism deterrence techniques and best practices to avoid plagiarism. They became aware of using anti-plagiarism software tools, they watched videos and animations that explained different forms of plagiarism and they played games that let them realize the importance of proper academic writing and they become aware of existing legislation that defines commercial online activity. A preliminary report on their assessment is included