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Existing research attempts to create realistic crowd simulations by incorporating personality and emotion into intelligent agents. However, personality and emotion were considered separately in existing studies, where the interactions of them are ignored. The main objective of this paper is to propose and implement a framework for crowd simulation with integration of the impacts and interactions of personality and emotion. An interactive solution based on the proposed framework is also developed for visualizing the crowd navigation behavior and collecting the related trajectory data. Three simulated scenarios: pass through, narrow passage, and emergence situation are used to validate the framework and compare the results with recent studies.