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This paper attempts to integrate concepts of e-marketplace and inter-organizational relationship to built a framework for influencing factors of e-business partnership and empirically explore it. The importance for five dimensions of the Research Model based on four top representatives of interviewed Taiwanese companies engaged in e-marketplaces is summarized. Fuzzy Delphi Method is used to decide which factors are vital for the success in three phases of partnership in e-marketplace. Data are collected through a survey of organizations that are actively involved in the planning or operation of e-marketplaces. Except exploiting of new market, the result has been shown the influencing factors are not the same in three phases of partnership in e-marketplace. It implies that to manage an e-marketplace must have different strategies to select, develop, and maintain participants.