Government regulation of business activity has been recognized as having critical impact on countries economic development. The aim of this research is to empirically explore the role played by information and communication technology (ICT) on the regulatory environment for doing business at the country level. We expect that the greater the access to information, the better the regulatory framework for doing business which can in turn have a positive impact on economic performance. Further, we intend to assess the extent to which ICT measures mediate the effect of business regulation on countries’ economic performance as measured by GDP per capita. This undergoing research is based on empirical evidence from two databases of the World Bank namely the Doing Business Database and the World Development Indicators database both of which had their most recent release in September 2008. Preliminary results using data corresponding to the year 2005 support our hypotheses.