This paper explores and conceptualises a phenomenon called platformization. The background is that the growing complexity of IT solutions is in many organizations costly and virtually impossible to adapt to changing organizational structures, strategies and user needs. IS research has so far failed to address this issue in full theoretical and practical breadth. Building on current research we suggest a framework for a promising approach; a platformization process. Our research question is, how can we transform an IT silo structure into a platform oriented digital infrastructure? The empirical evidence is a multilevel study of a large e-health initiative in Norway, where we analyse an emergent platformization process. We offer two contributions; first we give an outline of the key elements of a platformization strategy, second, we propose a new platform-oriented infrastructure configuration.