Gene testing emerged as a business in the last two decades, and the testing cost has been reduced from 100 million to 1000 dollars for the development of technologies. Preimplantation genetic screening (PGS) is a popular genetic profiling of embryos prior to implantation in gene testing. Copy number variants (CNVs) detection is a key task in PGS which still needs the manual operation and evaluation. At the same time, deep learning technology earns a booming development and wide application in recent years for its strong computing and learning capability. This research redesigns the PGS workflow with the intelligent CNVs detection system, and proposes the corresponding system framework. Deep learning is selected as the proper technology in the system design for CNVs detection, which also fit the task of denoising. The evaluation is conducted on simulation dataset with high accuracy and low time cost, which may achieve the requirements of clinical application and reduce the workload of bioinformatics experts. Moreover, the redesigned process and proposed framework may enlighten the intelligent system design for gene testing in following work, and provide a guidance of deep learning application in AI healthcare

CKM Lee, The Hong Kong Polytechnic University


According to data of Census and Statistics Department, freight transport and storage services contributed to 90% of the employment of logistics sector in the period from 2010 to 2014. Traditional warehouse operations in Hong Kong are labor-intensive without much automation. With the rapid increasing transaction volume through multi-channel, the preference for next-day delivery service has been increasing. As a result, 3rd party logistics providers have realized the importance of operational efficiency. With the advent of Industry 4.0 emerging technologies including Autonomous Robots, Industrial Internet of Things (IIoT), Cloud Computing, etc., a smart robotic warehouse management system is proposed as it redefines the warehouse put-away and picking operations from man-to-goods to goods-to-man using autonomous mobile robots. This paper aims to develop and implement an IIoT-based smart robotic warehouse system for managing goods and autonomous robots, as well as to make use of the autonomous mobile robots to deliver the goods automatically for put-away and picking operations. The significance of the paper is to leverage the Industry 4.0 emerging technologies to implement the concept of smart warehousing for better utilization of floor space and labor force so as to improve logistics operational efficiency