This paper aims to study how to embed interactive digital artifacts (such as blogs, wikis, videos, images, etc.) in information systems. These artifacts are unstable and in constant change challenging the traditional approaches to the management of information systems to which they are integrated. Institutions can no longer be seen as closed systems, but shall be construed as environments that expand in information networks and interaction and collaboration spaces for groups and society. Consequently, they become subject to interference from their cultural, behavioral, social and political environment. This research will focus on a case of a nation-wide information system for education, sharing of knowledge and assistance to dental professionals within government health teams. The expected contribution is a better understanding of the changes brought about in organizations and in information systems management processes resulting from the incorporation of interactive digital artifacts to those systems.