Although the adoption of information system (IS) packages offers many benefits over the development of custom-made IS, organizations often face severe difficulties in their adaptation to work processes embedded in the product and get unexpected and undesirable effects such as a decrease in IS post-adoption usage. By adopting organizational routines theory as its theoretical lens for interpreting results, this qualitative study’s goal is to better understand this adaptation process and how it relates to IS post-adoption behavior. This proposed dissertation should contribute to IS theory and practice by providing insights on: the effects of possible misfits between IS packages designed for large business organizations yet applied within less conventional organizations, the organizations’ internal dynamics as they adapt to work processes embedded in IS packages and their influence on IS package post-adoption behavior, and the role of technology’s material properties in organizational change and organizational routines.