Technology acceptance is one of the most extensive streams of research in the information systems literature. Building on previous work, it has recently been proposed that the gender of information system users moderates the relationships between intention to use a technology and its most important determinants, perceived usefulness and perceived ease of use. A better understanding of the magnitude of this effect and its implications seems important in the development of practical applications of the theory, such as those related to training and motivational interventions. This research reports on a preliminary meta-analysis of extant literature in mainstream journals employing the proportion of men and women in the studies as an indicator of the expected relationships. An explanation of this approach is provided, and preliminary results are discussed.