This study presents a conceptual model to investigate technology management competency required by healthcare IS professionals and its impacts on IT-healthcare partnerships. Technology management competency, at the broad level, comprises the business strategic thinking, external knowledge resources linkage, healthcare technology integration capability as well as management and interpersonal skill/knowledge possessed by IS professionals. Such competency is hypothesized to be instrumental in increasing the intentions of IS professionals to develop and reinforce the partnerships with healthcare people. The empirical results support the proposed conceptual framework for technology management related skills/knowledge of IS professionals and indicate that the competency would significantly influences the intentions of IS professionals to develop collaborative relationships with their healthcare partners. The findings of this study not only can provide useful suggestions to help IS professionals review their technology management competency, but also serve as instrumental guidelines for the technology management competency training to strength the IT-healthcare partnership.