The growth in electronic commerce has brought into focus the critical role of inter-organizational systems (IOS) in facilitating various aspects of business transactions between two companies. In the operations and logistics field, supply chain management (SCM) has been touted as one of the major strategies to improve organizational performance and generate competitive advantage. Although IOS are extensively used to facilitate SCM, very few papers have examined the inter-linkages between the two topics. Research has focused on the flow of material and information independently. In this paper we propose to integrate the two concepts, SCM and IOS, and identify management issues related to implementation of an electronic supply chain that integrates traditional supply chain with IOS.