This paper primarily examines the differences between how various users with different learning style preferences interact with computers in the global hypertext information network of the World Wide Web. Is it possible to design user interfaces that are equally effective for all the various computer users? This study was undertaken with two main goals in mind. Two aspects of research findings from empirical studies on usability of user interfaces on the World Wide Web are that: (1) it examines users who have varied styles of learning from visual, audio, to kinesthetic and their interactions with various user interfaces; and (2) it compares task performance, confidence, and satisfaction among various user interfaces on the Web. Implications of these results for various interfaces are discussed.