Grupo Columbia is a Mexican organization whose major business activity is related to the health care sector. The organization, facing a new global environment, establishes a corporate strategy for increasing its competitive position. Through this vision, Grupo Columbia finds information systems as the most suitable instrument for achieving its strategy.In order to implement the process, Grupo Columbia creates a profitable business unit called ColSis, seeking to encourage a culture of informatics in the health care sector. Furthermore, it defines among its activities the development of an information system to provide information about the whole spectrum of medical diagnoses for generating a nation-wide, permanently updated intelligent database used for sharing necessary information among various stakeholders within the health care sector, thus turning the project into a financially feasible one.