Organizational culture has been shown throughout the literature to significantly impact upon change, change management and change processes operating within organizations. Socio-Technical innovations such as Enterprise Systems (ES) bring significant change to organizations both during initial implementation, installation and subsequent use. Several researchers have attempted to define the role that national culture plays in the use of an Information System and research suggests that culture impacts ES success and reconfirms that culture impacts change processes. However, research, whilst indicating that organizational culture does play a role, fails to identify ‘how’ organisational culture affects these unique IT Innovations. This research addresses this gap, which is important for multinational corporations spanning multiple regions and industries. This paper reports on the design of the study investigating the relationship between organizational culture and IT innovation success in the context of extended ES.