Over a long period of time much research and development has been done on the use of Medical Information Technology, and many products have been developed for use by General Practitioners. However, despite this development effort, reluctance on behalf of GPs to use IT continue, particular with those GPs working in rural areas. This paper discusses adoption of IT by rural GPs and the methodological framework used in the research. It seeks to compare two theories of innovation that may assist in building a model of the socio- technical factors that act to enable, and to inhibit GPs’ uptake of technology