Previous research on the macroeconomic consequences of the development of information and communication technology (ICT) has produced mixed results. Despite the intense debate on the link between ICT and economic performance, there is no research that systematically takes the quality of domestic institutions into consideration. To address this issue, this study seeks to examine the effect of ICT penetration on economic performance by distinguishing countries with strong institutional qualities from those with weak institutional qualities. Using a pooled- OLS regression model and yearly data for the ASEAN-5 from 1991-2013, this study finds that there is a positive relationship between the penetration of ICT and economic performance. More importantly, this study also shows that while penetration of ICT is one of the key determinants of economic performance, better institutional quality does foster economic performance in ASEAN-5 economies.