The Internet provides access to a plethora of information, with health information being no exception. Portals for guiding users seeking health knowledge are proliferating. A major challenge in their development is filtering the information available in a user-sensitive way. The Breast Cancer Knowledge Online (BCKOnline) project addresses the challenge of meeting the diverse information needs of women with breast cancer and their families through the provision of timely, relevant and reliable information to support decision-making. This paper focuses on how the outcomes of user needs analysis and user-aware resource description will feed into building an intelligent portal prototype to breast cancer knowledge.